What may happen next to the pandemic H1N1 virus?
The following scenarios should be considered:
- re-appearance annually as a seasonal influenza virus
- co-circulation with human seasonal and avian influenza viruses (e.g. H5N1) may lead to reassortment between any of these viruses
- change of virulence through mutation or reassortment
- acquisition of antiviral resistance through mutation or reassortment
- introduction of a novel pandemic virus from the animal world